FB2026_03 , released September 17, 2026
Complex: SPLICEOSOME COMPLEX INTERMEDIATES
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General Information
Name
SPLICEOSOME COMPLEX INTERMEDIATES
Species
D. melanogaster
Symbol
SPL-INT
FlyBase ID
FBgg0000537
Date last reviewed
2016-09-05
Number of members
145
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome. The spliceosome is composed of five small nuclear ribonucleoprotein complexes, along with many associated protein cofactors, that assemble to catalyze the removal of introns from pre-mRNA and the joining of exons to produce mature mRNA. The spliceosome assembles in a step-wise manner, which have been described as the complex intermediates as components assemble and dissociate as the splicing cycle proceeds. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group

The SPLICEOSOME COMPLEX INTERMEDIATES gene groups have been assembled from a single source, the spliceosome database (http://spliceosomedb.ucsc.edu).

Only complex intermediates A, B, C and P have gene groups. The activated complexes, Bact and B*, and the early complex (E) have not been curated.

Source Material
The SPLICEOSOME COMPLEX INTERMEDIATES Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
spliceosomal complex
Related Gene Groups
Parent group(s)
SPLICEOSOMAL COMPLEXES
Component group(s)
SPLICEOSOME COMPLEX A
SPLICEOSOME COMPLEX B
SPLICEOSOME COMPLEX C
SPLICEOSOME COMPLEX P
Members (145)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SPL-INT
SPLICEOSOME COMPLEX INTERMEDIATES
Secondary FlyBase ID(s)
References (4)