Anoctamins (or TMEM16 family members) are calcium-activated chloride channels (CaCC) with eight putative transmembrane domains. It is not clear whether all anoctamins possess CaCC activity. (Adapted from FBrf0223235 and PMID:25451786).
Notes on Group
CG15270 is included in the ANOCTAMINS gene group based on its sequence similarity to other members of this family and the presence of an Anoctamin InterPro domain, but there is no published data to support its inclusion.