FB2026_03 , released September 17, 2026
Gene Group: CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS
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General Information
Name
CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS
Species
D. melanogaster
Symbol
CACC
FlyBase ID
FBgg0000558
Date last reviewed
2025-01-21
Number of members
11
Description
Description
The Calcium-activated chloride channels (CaCC) are activated by an increase in cytosolic calcium with outward rectification at low calcium levels. CaCC channels preferentially permeate larger anions and have a moderate selectivity for Cl-. (Adapted from FBrf0223235 and PMID:11099350).
Notes on Group
Source Material
The CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS Gene Group has been compiled using the following publication(s): Leung et al., 2024, Menzies et al., 2024, Jang et al., 2015, Chintapalli et al., 2013, Wong et al., 2013, Hartzell et al., 2008, Chien and Hartzell, 2007, Suzuki, 2006, Galindo and Vacquier, 2005, Tavsanli et al., 2001, and Ashburner et al., 1999.10.12 .
Key Gene Ontology (GO) terms
Molecular Function
chloride channel activity
Biological Process
chloride transmembrane transport
Cellular Component
membrane
Related Gene Groups
Parent group(s)
CALCIUM-ACTIVATED ION CHANNELS
CHLORIDE CHANNEL SUBUNITS
Component group(s)
ANOCTAMINS
BESTROPHINS
TWEETY FAMILY
Members (11)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
CACC
CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS
Secondary FlyBase ID(s)
References (12)