GABA-gated chloride channels mediate synaptic inhibition and regulate cellular excitability. GABA is the principal inhibitory neurotransmitter in the insect nervous system. Upon GABA binding the pore will open to allow chloride anions to pass, leading to hyperpolarization. (Adapted from FBrf0232136 and FBrf0228637).
Notes on Group
alka was moved from the GABA-GATED CHLORIDE CHANNEL SUBUNITS to the PH-SENSITIVE CHLORIDE CHANNEL SUBUNITS gene group based on experimental data in FBrf0256091.
