FB2026_02 , released June 18, 2026
Gene Group: HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS
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General Information
Name
HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS
Species
D. melanogaster
Symbol
HIS-CL
FlyBase ID
FBgg0000563
Date last reviewed
2025-01-21
Number of members
2
Description
Description
Histamine-gated chloride channels mediate synaptic inhibition and regulate cellular excitability. Histamine serves as a fast neurotransmitter in the visual system and some mechanosensory circuits of arthropods. (Adapted from FBrf0232136, FBrf0141682 and FBrf0205744).
Notes on Group
Source Material
The HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS Gene Group has been compiled using the following publication(s): Remnant et al., 2016, Knipple and Soderlund, 2010, Pantazis et al., 2008, Schnizler et al., 2005, Gisselmann et al., 2004, and Gisselmann et al., 2002 .
Key Gene Ontology (GO) terms
Molecular Function
histamine-gated chloride channel activity
Biological Process
chloride transmembrane transport
Cellular Component
histamine-gated chloride channel complex
plasma membrane
Related Gene Groups
Parent group(s)
LIGAND-GATED CHLORIDE CHANNEL SUBUNITS
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
HIS-CL
HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS
HisCl
Secondary FlyBase ID(s)
References (7)