Complex: N-TERMINAL ACETYLTRANSFERASE A COMPLEX

General Information

Name

N-TERMINAL ACETYLTRANSFERASE A COMPLEX

Species

D. melanogaster

Symbol

NATA

FlyBase ID

FBgg0000644

Date last reviewed

2024-04-22

Number of members

Description

The N-terminal acetyltransferase A (NatA) complex acetylates Ser-, Ala-, Thr-, Gly-, Val- and Cys- N-termini after the initiator methionine is removed. (Adapted from PMID:19660096, PMID:22405572).

Notes on Group

san is the ortholog of human NAA50 and encodes a putative N-acetyltransferase. It associates with the products of vnc and Naa15-16 in the NatA complex, and appears to be required for full NatA activity (FBrf0167411, FBrf0234437, PMID:16507339).

Source Material

The N-TERMINAL ACETYLTRANSFERASE A COMPLEX Gene Group has been compiled using the following publication(s): Rathore et al., 2016 and Williams et al., 2003 .

Key Gene Ontology (GO) terms

Molecular Function

protein-N-terminal amino-acid acetyltransferase activity

Biological Process

N-terminal protein amino acid acetylation

Cellular Component

NatA complex

Enzymatic activity

Enzyme name (EC)

N-terminal amino-acid N(alpha)-acetyltransferase NatA (2.3.1.255)

Related Gene Groups

Parent group(s)