FB2026_02 , released June 18, 2026
Gene Group: SLC9 FAMILY OF SODIUM/PROTON EXCHANGERS
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General Information
Name
SLC9 FAMILY OF SODIUM/PROTON EXCHANGERS
Species
D. melanogaster
Symbol
SLC9
FlyBase ID
FBgg0000677
Date last reviewed
2024-06-28
Number of members
5
Description
Description
The solute carrier family 9 (SLC9) members are Na+/H+ exchangers that maintain cellular pH by utilising the sodium gradient across the plasma membrane to extrude protons produced by metabolism. (Adapted from FBrf0229646).
Notes on Group
Source Material
The SLC9 FAMILY OF SODIUM/PROTON EXCHANGERS Gene Group has been compiled using the following publication(s): Chintapalli et al., 2015, Day et al., 2008, and Giannakou and Dow, 2001 .
Key Gene Ontology (GO) terms
Molecular Function
sodium:proton antiporter activity
Biological Process
regulation of intracellular pH
Cellular Component
plasma membrane
Related Gene Groups
Parent group(s)
TRANSMEMBRANE CARRIER PROTEINS
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SLC9
Na+/H+ exchangers
sodium/proton exchangers
sodium/proton antiporters
NHE
NHA
SLC9 FAMILY OF SODIUM/PROTON EXCHANGERS
SOLUTE CARRIER FAMILY 9
Secondary FlyBase ID(s)
References (4)