Gene Group: HOMEOBOX TRANSCRIPTION FACTORS

General Information

Name

HOMEOBOX TRANSCRIPTION FACTORS

Species

D. melanogaster

Symbol

HBTF

FlyBase ID

FBgg0000744

Date last reviewed

2017-06-19

Number of members

102

Description

Homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. These family members are characterized by a helix-turn-helix DNA-binding motif known as the homeodomain (encoded by the 180 bp homeobox sequence element). The homeobox transcription factors are a diverse group, many of which play important roles in embryonic development. (Adapted from FBrf0232555, PMID:11470884 and PMID:17963489).

Notes on Group

The HOMEOBOX TRANSCRIPTION FACTORS have been divided into sub-groups based on phylogenetic analysis presented in FBrf0232555 and PMID:11470884.

Source Material

The HOMEOBOX TRANSCRIPTION FACTORS Gene Group has been compiled using the following publication(s): Bürglin and Affolter, 2016, Zhong and Holland, 2010, Demidenko et al., 2001, Popovici et al., 2001, Breitling and Gerber, 2000, Hobert and Westphal, 2000, Kawakami et al., 2000, Galliot et al., 1999, Billin et al., 1991, and Kim and Nirenberg, 1989 .

Key Gene Ontology (GO) terms

Molecular Function

DNA-binding transcription factor activity

transcription cis-regulatory region binding

Biological Process

regulation of DNA-templated transcription

Cellular Component

nucleus

Related Gene Groups

Parent group(s)

HELIX-TURN-HELIX TRANSCRIPTION FACTORS

Component group(s)