FB2026_03 , released September 17, 2026
Gene Group: FORK HEAD BOX TRANSCRIPTION FACTORS
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General Information
Name
FORK HEAD BOX TRANSCRIPTION FACTORS
Species
D. melanogaster
Symbol
FOX
FlyBase ID
FBgg0000750
Date last reviewed
2017-06-22
Number of members
19
Description
Description
The forkhead box family of transcription factors are sequence-specific DNA binding proteins that regulate transcription. They are characterized by approximately 110 amino acid DNA-binding domain known as the forkhead or winged helix. (Adapted from FBrf0173142).
Notes on Group
Source Material
The FORK HEAD BOX TRANSCRIPTION FACTORS Gene Group has been compiled using the following publication(s): Janssen et al., 2022, Schomburg et al., 2022, Pfreundt et al., 2010, Lee and Frasch, 2004, and Mazet et al., 2003 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity
transcription cis-regulatory region binding
Biological Process
regulation of DNA-templated transcription
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
HELIX-TURN-HELIX TRANSCRIPTION FACTORS
Members (19)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
FOX
FORK HEAD BOX TRANSCRIPTION FACTORS
Winged helix-turn-helix factors
Forkhead transcription factors
Winged-helix transcription factors
FOX proteins
Secondary FlyBase ID(s)
References (6)