FB2026_03 , released September 17, 2026
Gene Group: MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS
Open Close
General Information
Name
MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS
Species
D. melanogaster
Symbol
MHTF
FlyBase ID
FBgg0000770
Date last reviewed
2017-11-08
Number of members
4
Description
Description
The Mother against Dpp (MAD) homology (MH) domain transcription factors are sequence-specific DNA-binding proteins that regulate transcription. These members contain an N-terminal sequence-specific DNA-binding MH1 and a C-terminal MH2 domain that mediates the formation of oligomeric complexes. (Adapted from FBrf0208242 and FBrf0206210).
Notes on Group
Source Material
The MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS Gene Group has been compiled using the following publication(s): Hammonds et al., 2013 and Li et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity
transcription cis-regulatory region binding
Biological Process
regulation of DNA-templated transcription
transforming growth factor beta receptor signaling pathway
Cellular Component
nucleus
cytosol
Related Gene Groups
Parent group(s)
TRANSCRIPTION FACTORS
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
MHTF
MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS
smad
Secondary FlyBase ID(s)
References (3)