FB2026_03 , released September 17, 2026
Complex: HYPOXIA-INDUCIBLE FACTOR
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General Information
Name
HYPOXIA-INDUCIBLE FACTOR
Species
D. melanogaster
Symbol
HIF
FlyBase ID
FBgg0000902
Date last reviewed
2023-08-08
Number of members
2
Description
Description
Hypoxia-inducible factor (HIF) mediates hypoxia-dependent transcription. It is a heterodimeric basic helix-loop-helix transcription factor complex composed of a constitutively expressed HIF-β subunit and an oxygen-regulated HIF-α subunit. (Adapted from FBrf0190953).
Notes on Group
Source Material
The HYPOXIA-INDUCIBLE FACTOR Gene Group has been compiled using the following publication(s): Dekanty et al., 2005 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription cis-regulatory region binding
Biological Process
positive regulation of transcription by RNA polymerase II
Cellular Component
RNA polymerase II transcription regulator complex
Related Gene Groups
Other related group(s)
INSULIN-LIKE RECEPTOR SIGNALING PATHWAY CORE COMPONENTS
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
HIF
HYPOXIA-INDUCIBLE FACTOR
Secondary FlyBase ID(s)
References (2)