Complex: CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX

General Information

Name

CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX

Species

D. melanogaster

Symbol

PI3K-IA

FlyBase ID

FBgg0000903

Date last reviewed

2024-04-23

Number of members

Description

Class IA phosphoinositide 3-kinase (PI3K) is a heterodimeric complex of a regulatory and catalytic subunit and is a core component of many many signaling pathways. In vitro, PI3Ks can phosphorylate phosphatidylinositol (PtdIns), PtdIns(4)P and PtdIns(4,5)P2 to generate PtdIns(3)P, PtdIns(3,4)P2 and PtdIns(3,4,5)P3, respectively. (Adapted from PMID:24587488 and FBrf0227909).

Notes on Group

Source Material

The CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX Gene Group has been compiled using the following publication(s): Breitkopf et al., 2016, Balakrishnan et al., 2015, and Weinkove et al., 1997 .

Key Gene Ontology (GO) terms

Molecular Function

phosphatidylinositol kinase activity

Biological Process

Cellular Component

phosphatidylinositol 3-kinase complex, class IA

Related Gene Groups

Other related group(s)

INSULIN-LIKE RECEPTOR SIGNALING PATHWAY CORE COMPONENTS

Members (2)

For all members:

GO ribbon stack