FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: NEPRILYSIN-LIKE METALLOENDOPEPTIDASES
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General Information
Name
NEPRILYSIN-LIKE METALLOENDOPEPTIDASES
Species
D. melanogaster
Symbol
NEPL
FlyBase ID
FBgg0000964
Date last reviewed
2018-07-19
Number of members
21
Description
Description
The Neprilysin-like metallopeptidases belong to the M13 family of metalloproteases. They show significant similarity to vertebrate and Drosophila Neprilysins but lack one or more of the conserved motifs important for catalytic activity, indicating they are likely inactive peptidases. (Adapted from FBrf0239474.)
Notes on Group
Source Material
The NEPRILYSIN-LIKE METALLOENDOPEPTIDASES Gene Group has been compiled using the following publication(s): Meyer et al., 2021, Meyer et al., 2018.7.18, Sitnik et al., 2014, Bland et al., 2008, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
M13 METALLOENDOPEPTIDASES
METALLO-TYPE NON-PEPTIDASE HOMOLOGS
Members (21)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
NEPL
NEPRILYSIN-LIKE METALLOENDOPEPTIDASES
Secondary FlyBase ID(s)
References (6)