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General Information
Name
Pvr Signaling Pathway Core Components
Species
D. melanogaster
Symbol
PVR-C
FlyBase ID
FBgg0000973
Date last reviewed
2020-01-06
Number of members
30
Description
Description
PDGF/VEGF (Platelet-Derived Growth Factor/Vascular Endothelial Growth Factor)-receptor related (Pvr) encodes a receptor tyrosine kinase activated by the binding of PDGF- and VEGF-related factors (Pvf1,Pvf2 or Pvf3). Pvr has been shown to activate the canonical Ras/Raf/MAP kinase (ERK) cascade, the PI3K kinase pathway, TORC1 (FBrf0222697), Rho family small GTPases (FBrf0221764, FBrf0180198) and the JNK cascade (FBrf0180198), in a context-dependent manner. (Adapted from FBrf0222697 and FBrf0221727).
Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
Related Gene Groups
Parent group(s)
Physical Interaction Network
Members (30)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PVR-C
Pvr Signaling Pathway Core Components
Platelet-Derived Growth Factor-Vascular Endothelial Growth Factor Receptor-Related Signaling Pathway Core Components
Secondary FlyBase ID(s)
References (16)