FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

vascular endothelial growth factor receptor signaling pathway

ID (Ontology)

GO:0048010 (Gene Ontology)

Definition

The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

Also Known As

"VEGF receptor signaling pathway" ; "VEGF receptor signalling pathway" ; "VEGFR signaling pathway"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
vascular endothelial growth factor receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)
involved_in \| vascular endothelial growth factor receptor signaling pathway	--

Spanning Tree (Parents/Children)

  enzyme-linked receptor protein signaling pathway
   |__cell surface receptor protein tyrosine kinase signaling pathway
       |__vascular endothelial growth factor receptor signaling pathway  44 rec.
           |__positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
           |__regulation of vascular endothelial growth factor receptor signaling pathway 10 rec.
           |   |__negative regulation of vascular endothelial growth factor receptor signaling pathway 8 rec.
           |   |__positive regulation of vascular endothelial growth factor receptor signaling pathway 2 rec.
           |__vascular endothelial growth factor receptor-1 signaling pathway
           |__vascular endothelial growth factor receptor-2 signaling pathway
           |__vascular endothelial growth factor receptor-3 signaling pathway

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cell surface receptor protein tyrosine kinase signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"VEGF receptor signaling pathway" EXACT "VEGF receptor signalling pathway" EXACT "VEGFR signaling pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-194138 "Signaling by VEGF"