FB2026_02 , released June 18, 2026
Gene Group: FERROXIDASES
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General Information
Name
FERROXIDASES
Species
D. melanogaster
Symbol
FOXS
FlyBase ID
FBgg0001030
Date last reviewed
2018-10-31
Number of members
6
Description
Description
Ferroxidases are a group of oxidoreductases that catalyze the oxidation of ferrous (Fe+2) iron to ferric (Fe+3) iron.
Notes on Group

Of the four genes encoding multicopper oxidases (which are candidate ferroxidases): stw encodes a laccase and is not included here; Mco1 and Mco3 have proven/predicted ferroxidase activity and are included here; Mco4 has not yet been characterized but is also included here. Of the 3 genes encoding ferritin subunits: heavy chain homologs (Fer1HCH and Fer3HCH) have ferroxidase activity, whereas light chain homologs (Fer2LCH) do not. (Reviewed in FBrf0222822.)

Source Material
The FERROXIDASES Gene Group has been compiled using the following publication(s): Tang and Zhou, 2013 and Dunkov and Georgieva, 2006 .
Key Gene Ontology (GO) terms
Molecular Function
ferroxidase activity
Biological Process
Cellular Component
Enzymatic activity
Enzyme name (EC)
ferroxidase (1.16.3.1)
Related Gene Groups
Parent group(s)
METAL ION OXIDOREDUCTASES
Other related group(s)
MULTICOPPER OXIDASES
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
FOXS
FERROXIDASES
Secondary FlyBase ID(s)
References (4)