FB2026_02 , released June 18, 2026
Gene Group: PEPTIDYL-PROLINE DIOXYGENASES
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General Information
Name
PEPTIDYL-PROLINE DIOXYGENASES
Species
D. melanogaster
Symbol
PPDOX
FlyBase ID
FBgg0001042
Date last reviewed
2025-10-29
Number of members
27
Description
Description
Peptidyl-proline dioxygenases catalyze the hydroxylation of peptidyl L-proline to peptidyl hydroxy-L-proline, where 2-oxoglutarate and one other act as hydrogen or electron donors with incorporation of one atom of oxygen into each donor.
Notes on Group

CG34041 lacks a prolyl hydroxylase catalytic domain and is therefore omitted from this group (FBrf0263596).

Source Material
The PEPTIDYL-PROLINE DIOXYGENASES Gene Group has been compiled using the following publication(s): Ishikawa et al., 2025 and Abrams and Andrew, 2002 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Members (27)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
PPDOX
PEPTIDYL-PROLINE DIOXYGENASES
Prolyl 4-hydroxylases
PH4
Secondary FlyBase ID(s)
References (4)