FB2026_03 , released September 17, 2026
Gene Group: ATG8/12 ACTIVATING ENZYMES
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General Information
Name
ATG8/12 ACTIVATING ENZYMES
Species
D. melanogaster
Symbol
ATGAE
FlyBase ID
FBgg0001230
Date last reviewed
2019-11-08
Number of members
1
Description
Description
ATG8/12 activating enzymes are 'non-canonical' E1 enzymes that form obligate homodimers and activate the ubiquitin-like proteins ATG8 and ATG12 for subsequent steps along their respective conjugation cascades. (Adapted from PMID:28234446.)
Notes on Group
Source Material
The ATG8/12 ACTIVATING ENZYMES Gene Group has been compiled using the following publication(s): Du et al., 2011 .
Key Gene Ontology (GO) terms
Molecular Function
Atg8 activating enzyme activity
Atg12 activating enzyme activity
Biological Process
protein modification by small protein conjugation
Cellular Component
Related Gene Groups
Parent group(s)
E1 UBIQUITIN-LIKE ACTIVATING ENZYMES
Other related group(s)
ATG8 TRANSFERASES
ATG12 TRANSFERASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
ATGAE
ATG8/12 ACTIVATING ENZYMES
Secondary FlyBase ID(s)
References (3)