FB2026_02 , released June 18, 2026
Gene Group: PSEUDO-PYRUVATE KINASES
Open Close
General Information
Name
PSEUDO-PYRUVATE KINASES
Species
D. melanogaster
Symbol
PSPYK
FlyBase ID
FBgg0001264
Date last reviewed
2025-03-10
Number of members
5
Description
Description
Pseudo-pyruvate kinases show homology to pyruvate kinase but lack key functional residues for this activity. (Adapted from FBrf0261725.)
Notes on Group

*u There are six paralogous genes encoding pyruvate kinase in D. melanogaster: expression of Pyk is ubiquitous and the encoded enzyme is functional; in contrast, expression of Pykl1, Pykl2, Pykl3, Pykl4 and Pykl5 is restricted to the testis and the encoded proteins are predicted to be catalytically inactive. (FBrf0261725)

Source Material
The PSEUDO-PYRUVATE KINASES Gene Group has been compiled using the following publication(s): Zaru and Marygold, 2025 and Heidarian et al., 2023 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
PSEUDOKINASES
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
PYRUVATE KINASES
PSEUDO-PYRUVATE KINASES
PSPYK
PYK
Secondary FlyBase ID(s)
References (4)