CDC25 phosphatases are tyrosine phosphatases that play critical roles in mitosis. The family is represented in Drosophila by the paralogous genes
stg and
twe.
stg plays a role at the start of mitotic events during embryogenesis, oogenesis and regulates proliferation and stem cell maintenance, whereas
twe plays a role in meiosis and oogenesis. (Adapted from
FBrf0227974.)