Gene Group: MACROMOLECULAR CONFORMATION ISOMERASES

General Information

Name

MACROMOLECULAR CONFORMATION ISOMERASES

Species

D. melanogaster

Symbol

MCISO

FlyBase ID

FBgg0001730

Date last reviewed

2022-06-20

Number of members

152

Description

Macromolecular conformation isomerases alter the conformation of macromolecules, such as polypeptides, DNA or RNA. Most are ATPases and use energy derived from ATP hydrolysis to drive the conformational change. They include motor proteins (myosins, kinesins, dyneins), proteasome regulatory particle ATPases, microtubule severing ATPases, helicases and DNA topoisomerases.

Notes on Group

The MACROMOLECULAR CONFORMATION ISOMERASES group corresponds to EC:5.6.-.-.

Source Material

The MACROMOLECULAR CONFORMATION ISOMERASES Gene Group has been compiled using the following publication(s): Cox et al., 2019, Holsclaw and Sekelsky, 2017, Tao et al., 2016, Hoskins et al., 2015, Karak et al., 2015, Kollmar, 2015.9.15, Kassavetis and Kadonaga, 2014, Moy et al., 2014, Hirokawa, 2012, Hirokawa, 2012.11.20, Dyer et al., 2011, Huen et al., 2010, Ulvila et al., 2010, Belote and Zhong, 2009, Odronitz et al., 2009, Diop et al., 2008, Crevel et al., 2007, Wickstead and Gull, 2007, Zhang et al., 2007, Pfister et al., 2006, Blanton et al., 2005, Miki et al., 2005, Dagenbach and Endow, 2004, Goshima and Vale, 2003, Ma et al., 2002, Tzolovsky et al., 2002, Berg et al., 2001, Boudet et al., 2001, Miki et al., 2001, Sanjuan and Marin, 2001, Bauer et al., 2000, de Carvalho et al., 2000, Goldstein and Gunawardena, 2000, Lasko, 2000, Sekelsky et al., 2000, Yamashita et al., 2000, Kurek et al., 1998, and Rasmusson et al., 1994 .

Key Gene Ontology (GO) terms

Molecular Function

macromolecular conformation isomerase activity

Biological Process

Cellular Component

Enzymatic activity

Enzyme name (EC)

5.6.-.-

Related Gene Groups

Parent group(s)

ISOMERASES

Component group(s)