FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: ATG12 PROTEINS
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General Information
Name
ATG12 PROTEINS
Species
D. melanogaster
Symbol
ATG12
FlyBase ID
FBgg0001758
Date last reviewed
2021-08-02
Number of members
1
Description
Description
Atg12 is a ubiquitin-like protein that is conjugated to Atg5 by Atg7 (an E1-like protein) and Atg10 (an E2-like protein). The Atg12-Atg5 conjugate localizes to the developing autophagosome where it acts as an E3-like enzyme to facilitate the lipidation of Atg8 (another ubiquitin-like protein) and direct its correct subcellular localization. (Adapted from PMID:18704115 and PMID:31901645.)
Notes on Group

The ATG12 PROTEINS gene group contains only one member.

Source Material
The ATG12 PROTEINS Gene Group has been compiled using the following publication(s): Nagy et al., 2015 and Zirin and Perrimon, 2010 .
Key Gene Ontology (GO) terms
Molecular Function
protein tag activity
Biological Process
protein modification by small protein conjugation
Cellular Component
Related Gene Groups
Parent group(s)
UBIQUITIN-LIKE PROTEINS
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
ATG12
ATG12 PROTEINS
Secondary FlyBase ID(s)
References (3)