Gene Group: UBIQUITIN-LIKE PROTEINS

General Information

Name

UBIQUITIN-LIKE PROTEINS

Species

D. melanogaster

Symbol

UBL

FlyBase ID

FBgg0001751

Date last reviewed

2021-08-02

Number of members

Description

Ubiquitin-like proteins (UBLs) include ubiquitin and other evolutionarily related proteins that share the ubiquitin fold and the capacity to be conjugated to substrates through a cascade of E1 activating enzymes, E2 conjugating enzymes, and E3 ligases. Conjugation of UBLs to target proteins or lipids regulate their activity, stability, subcellular localization, or macromolecular interactions. (Adapted from PMID:28234446.)

Notes on Group

D. melanogaster lacks homologs of the mammalian Ubiquitin-like proteins FAT10 and ISG15.

Source Material

The UBIQUITIN-LIKE PROTEINS Gene Group has been compiled using the following publication(s): Yu et al., 2020, Khoshnood et al., 2017, Pirone et al., 2017, Duan et al., 2016, Khoshnood et al., 2016, Ureña et al., 2016, Nagy et al., 2015, Lu et al., 2013, Smith et al., 2012, Zhan et al., 2012, Hoe et al., 2011, Zirin and Perrimon, 2010, Nie et al., 2009, Marygold, 2007.1.12, Ou et al., 2002, Shih et al., 2002, Bhaskar et al., 2000, and Izquierdo, 1994 .

Key Gene Ontology (GO) terms

Molecular Function

protein tag activity

Biological Process

protein modification by small protein conjugation

Cellular Component

Related Gene Groups

Component group(s)