FB2026_02 , released June 18, 2026
Gene Group: TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS
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General Information
Name
TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS
Species
D. melanogaster
Symbol
MA63
FlyBase ID
FBgg0001884
Date last reviewed
2023-11-22
Number of members
1
Description
Description
The TMEM63 (animal)/OSCA (plant) multi-pass transmembrane proteins are mechanically-activated, non-selective cation channels. (Adapted from PMID:37543036.)
Notes on Group

The OSCA/TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS gene group contains only one member.

Source Material
The TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS Gene Group has been compiled using the following publication(s): Li et al., 2022, Hehlert et al., 2021, Li and Montell, 2021, Jin et al., 2020, and Murthy et al., 2018 .
Key Gene Ontology (GO) terms
Molecular Function
mechanosensitive monoatomic cation channel activity
Biological Process
monoatomic cation transmembrane transport
Cellular Component
membrane
Related Gene Groups
Parent group(s)
MECHANOSENSITIVE ION CHANNEL SUBUNITS
NON-SELECTIVE CATION CHANNEL SUBUNITS
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
MA63
TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS
OSCA/TMEM63 stretch-activated ion channels
OSCA/TMEM63 family
OSCA/TMEM63 mechanosensitive ion channels
TMEM63 mechanosensitive ion channels
Secondary FlyBase ID(s)
References (6)