FB2026_02 , released June 18, 2026
Gene Group: TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS
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General Information
Name
TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS
Species
D. melanogaster
Symbol
TMCL
FlyBase ID
FBgg0001885
Date last reviewed
2023-11-22
Number of members
1
Description
Description
Transmembrane channel-like proteins are putative mechanically-activated, non-selective cation channels. (Adapted from PMID:37543036 and FBrf0246684.)
Notes on Group

The TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS gene group contains only one member.

Tmc is a putative mechanosensitive ion channel. A direct assay of mechanically-activated ion channel activity has not yet been demonstrated (FBrf0244023).

Source Material
The TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS Gene Group has been compiled using the following publication(s): Hehlert et al., 2021, Guo et al., 2020, Jin et al., 2020, and Yapici, 2020 .
Key Gene Ontology (GO) terms
Molecular Function
mechanosensitive monoatomic cation channel activity
Biological Process
monoatomic cation transmembrane transport
Cellular Component
membrane
Related Gene Groups
Parent group(s)
MECHANOSENSITIVE ION CHANNEL SUBUNITS
NON-SELECTIVE CATION CHANNEL SUBUNITS
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
TMCL
Transmembrane channel-like proteins
TMC mechanosensitive ion channels
TMC proteins
TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS
Secondary FlyBase ID(s)
References (5)