FB2026_03 , released September 17, 2026
Gene Group: MPV17/PMP22 CHANNEL FAMILY
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General Information
Name
MPV17/PMP22 CHANNEL FAMILY
Species
D. melanogaster
Symbol
PMP22-MPV17
FlyBase ID
FBgg0001965
Date last reviewed
2024-05-13
Number of members
10
Description
Description
The Mpv17/PMP22 (Mitochondrial inner membrane protein MPV17/Peroxisomal membrane protein 22) is a family of putative pore/channel-forming proteins. This family is not well-characterised, but members are generally thought to act as non-selective ion channels/pores with a slight preference for cations. (Adapted from PMID:11590176, PMID:25861990, FBrf0257754 and FBrf0255401.)
Notes on Group

The MPV17/PMP22 PUTATIVE MITOCHONDRIAL CHANNEL FAMILY members have been placed in a 'mitochondrial' subgroup of the 'MPV17/PMP22 CHANNEL FAMILY' based on orthology with vertebrate MPV17, MPV17L or MPV17L2.

Source Material
The MPV17/PMP22 CHANNEL FAMILY Gene Group has been compiled using the following publication(s): Corrà et al., 2023 .
Key Gene Ontology (GO) terms
Molecular Function
monoatomic ion channel activity
Biological Process
monoatomic ion transmembrane transport
Cellular Component
organelle membrane
Related Gene Groups
Parent group(s)
NON-SELECTIVE CATION CHANNEL SUBUNITS
Component group(s)
MPV17/PMP22 PUTATIVE MITOCHONDRIAL CHANNEL FAMILY
MPV17/PMP22 PUTATIVE PEROXISOMAL CHANNEL FAMILY
Members (10)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
PMP22-MPV17
MPV17/PMP22 CHANNEL FAMILY
Secondary FlyBase ID(s)
References (2)