FB2026_02 , released June 18, 2026
Complex: DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT
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General Information
Name
DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT
Species
D. melanogaster
Symbol
DRM-R
FlyBase ID
FBgg0001982
Date last reviewed
2024-06-27
Number of members
10
Description
Description
The DREAM complex is a MuvB-type transcriptional repressor complex containing multiple site-specific DNA-binding proteins, including E2f2 and Rbf. (Adapted from PMID:35468940 and FBrf0258562.)
Notes on Group

Note that the nomenclature and acronyms for MuvB-containing complexes makes it easy to confuse the complexes. We have adopted the nomenclature used by Complex Portal, where 'DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX' refers to the nine subunit, large assembly that includes E2F, pRb family and Myb proteins.

The DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT was sourced from Complex Portal, curated by EMBL-EBI.

Source Material
The DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT Gene Group has been compiled using the following publication(s): Hoareau et al., 2024 and Beall et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
sequence-specific DNA binding
DNA-binding transcription factor activity
Biological Process
negative regulation of DNA-templated transcription
Cellular Component
DRM complex
nucleus
Related Gene Groups
Parent group(s)
MUVB COMPLEXES
Members (10)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
DRM-R
dREAM
DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT
DREAM complex, Rbf variant
Drosophila RBF, dE2F2, and dMyb-interacting proteins
Secondary FlyBase ID(s)
References (3)