FB2026_03 , released September 17, 2026
Gene Group: ATYPICAL PROTEIN KINASE C SUBFAMILY
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General Information
Name
ATYPICAL PROTEIN KINASE C SUBFAMILY
Species
D. melanogaster
Symbol
APKC
FlyBase ID
FBgg0001990
Date last reviewed
2025-01-07
Number of members
1
Description
Description
The Protein Kinase C (PKC) family are serine/threonine kinases regulated by auto-inhibition through a pseudosubstrate site located in the regulatory domain. Unlike other members of the PKC family, atypical PKC (aPKC) subfamily are insensitive to diacylglycerol and Ca[2+] and are activated by protein-protein interactions. (Adapted from PMID:20094051 and FBrf0152086).
Notes on Group

The ATYPICAL PROTEIN KINASE C SUBFAMILY gene group contains only one member.

Source Material
The ATYPICAL PROTEIN KINASE C SUBFAMILY Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, Shieh et al., 2002, and Morrison et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
protein serine/threonine kinase activity
Biological Process
Cellular Component
Enzymatic activity
Enzyme name (EC)
2.7.11.-
Related Gene Groups
Parent group(s)
PROTEIN KINASE C FAMILY
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
APKC
ATYPICAL PROTEIN KINASE C SUBFAMILY
Secondary FlyBase ID(s)
References (5)