FB2026_02 , released June 18, 2026
Complex: DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX
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General Information
Name
DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX
Species
D. melanogaster
Symbol
DHDDSC
FlyBase ID
FBgg0001997
Date last reviewed
2024-08-07
Number of members
2
Description
Description
The dehydrodolichyl diphosphate synthase complex catalyzes cis-prenyl chain elongation to produce the poly-prenyl backbone of dolichol. It is composed of two subunits - DHDDS and NUS1 (aka NgBR or Tango14). Although DHDDS is considered the catalytically active subunit, both subunits are necessary for efficient dolichol synthesis. (Adapted from FBrf0249573.)
Notes on Group
Source Material
The DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX Gene Group has been compiled using the following publication(s): Brandwine et al., 2021 .
Key Gene Ontology (GO) terms
Molecular Function
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
Biological Process
dolichyl monophosphate biosynthetic process
Cellular Component
dehydrodolichyl diphosphate synthase complex
Enzymatic activity
Enzyme name (EC)
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] (2.5.1.87)
Related Gene Groups
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
DHDDSC
DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX
Secondary FlyBase ID(s)
References (2)