FB2026_02 , released June 18, 2026
Pathway: UDP-GLUCURONATE BIOSYNTHESIS
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General Information
Name
UDP-GLUCURONATE BIOSYNTHESIS
Species
D. melanogaster
Symbol
UDPGAB
FlyBase ID
FBgg0002049
Date last reviewed
2024-11-20
Number of members
3
Description
Description
The synthesis of the nucleotide-sugar UDP-glucuronate (UDP-GlcA) occurs in the cytosol and is produced from UDP-glucose. UDP-GlcA is then translocated into the Golgi apparatus via the frc transporter where it is used as a precursor for the biosynthesis of glycosaminoglycans and UDP-xylose. In D. melanogaster, UDP-GlcA is not involved in glucuronidation, a detoxification process of toxic metabolites that occurs in mammals. (Adapted from PMID:32749901.)
Notes
Source Material
The UDP-GLUCURONATE BIOSYNTHESIS Gene Group has been compiled using the following publication(s): Goto et al., 2001 and Benevolenskaya et al., 1998 .
Key Gene Ontology (GO) terms
Biological Process
UDP-glucuronate biosynthetic process
Cellular Component
cytosol
Related Gene Groups
Parent group(s)
NUCLEOTIDE-SUGAR BIOSYNTHESIS
GO Causal Activity Model (GO-CAM)
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Note: The Drosophila pathways shown at external resources are computed and may therefore differ from the manually curated and verified pathway shown above.
665912ed00002359
Synonyms and Secondary IDs
Synonym(s)
UDPGAB
UDP-GLUCURONATE BIOSYNTHESIS
Secondary FlyBase ID(s)
References (4)