In trehalose catabolism, trehalase Treh converts trehalose, a non-reducing disaccharide in the hemolymph, into 2 molecules of glucose. Trehalose can be hydrolyzed directly in the hemolymph by the Treh secreted isoform and the glucose produced can then be imported into cells. Alternatively, trehalose can be imported into the cell via the Tret1 transporter where it is cleaved by the Treh cytosolic isoform. (Adapted from FBrf0245354 and PMID:25429048.)