Complex: METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX

General Information

Name

METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX

Species

D. melanogaster

Symbol

METWD

FlyBase ID

FBgg0002114

Date last reviewed

2025-05-28

Number of members

Description

The METTL1-WUHO tRNA (guanine-N(7)-)-methyltransferase complex modifies guanosine to N[7]-methylguanosine (m[7]G) in the variable loop region of tRNAs that contain the 5'-RAGGU-3' motif. (Adapted from FBrf0260508.)

Notes on Group

The METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX was sourced from Complex Portal, curated by EMBL-EBI.

Source Material

The METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX Gene Group has been compiled using the following publication(s): Kaneko et al., 2024 .

Key Gene Ontology (GO) terms

Molecular Function

tRNA (guanine(46)-N7)-methyltransferase activity

Biological Process

tRNA methylation

Cellular Component

tRNA (m7G46) methyltransferase complex

Enzymatic activity

Enzyme name (EC)

tRNA (guanine(46)-N(7))-methyltransferase (2.1.1.33)

Related Gene Groups

Members (2)