Complex: CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT

General Information

Name

CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT

Species

D. melanogaster

Symbol

RPS-T

FlyBase ID

FBgg0002129

Date last reviewed

2025-06-09

Number of members

Description

Cytoplasmic ribosomes are found on the endoplasmic reticulum and in the cytosol. They translate all mRNAs produced from nuclear genes and perform the majority of cellular protein synthesis. Ribosomes are formed by two ribonucleoprotein subunits, large and small. The principle function of the small subunit is to bind mRNA. Tissue expression data from modENCODE has been used to infer the composition of the cytosolic small ribosomal subunit testis-specific variant. (Adapted from FBrf0205398.)

Notes on Group

Cytoplasmic rRNAs are multicopy genes organised in tandem arrays (FBrf0202637). 18S rRNA (18SrRNA, SO:0002236) is associated with the small cytoplasmic ribosome.

In yeast, the majority of ribosomal proteins have paralogs due to genome duplications. In D.mel, six subunits of the cytosolic small ribosome are encoded by paralogs (RpS10a/RpS10b, RpS14a/RpS14b, RpS15Aa/RpS15Ab, RpS19a/RpS19b, RpS28-like/RpS28a/RpS28b and RpS5a/RpS5b). Of these, four genes display a testis-specific expression profile (RpS10a, RpS19b, RpS28-like and RpS28a). RpS5b has a strong, but not exclusive, bias for expression in the ovary.

Source Material

The CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT Gene Group has been compiled using the following publication(s): Anger et al., 2013, Marygold et al., 2007, and Alonso and Santaren, 2006 .

Key Gene Ontology (GO) terms

Molecular Function

structural constituent of ribosome

Biological Process

cytoplasmic translation

Cellular Component

cytosol

cytosolic small ribosomal subunit

Related Gene Groups

Parent group(s)

CYTOPLASMIC RIBOSOMAL SUBUNITS

Members (37)