FB2026_02 , released June 18, 2026
Complex: NUCLEAR EXOSOME TARGETING COMPLEX
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General Information
Name
NUCLEAR EXOSOME TARGETING COMPLEX
Species
D. melanogaster
Symbol
NEXT
FlyBase ID
FBgg0002165
Date last reviewed
2026-01-09
Number of members
3
Description
Description
The nuclear exosome targeting (NEXT) complex is an RNA helicase complex that directs non-functional transcripts the nuclear exosome for degradation. (Adapted from PMID:35688157.)
Notes on Group
Source Material
The NUCLEAR EXOSOME TARGETING COMPLEX Gene Group has been compiled using the following publication(s): Lee et al., 2025 and Hu et al., 2017.6.13 .
Key Gene Ontology (GO) terms
Molecular Function
RNA helicase activity
Biological Process
nuclear RNA surveillance
Cellular Component
nuclear exosome targeting complex
nucleus
Enzymatic activity
Enzyme name (EC)
RNA helicase (3.6.4.13)
Related Gene Groups
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
NEXT
NUCLEAR EXOSOME TARGETING COMPLEX
NEXT complex
Secondary FlyBase ID(s)
References (3)