FB2026_02 , released June 18, 2026
Gene Group: PRELI-DOMAIN PROTEINS
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General Information
Name
PRELI-DOMAIN PROTEINS
Species
D. melanogaster
Symbol
PRELID
FlyBase ID
FBgg0002191
Date last reviewed
2026-03-13
Number of members
3
Description
Description
The PRELI domain-containing proteins are characterised by a conserved N-terminal ~170 amino acid domain. Localized to the mitochondrial intermembrane space (IMS), they shuttle specific phospholipids across the aqueous phase between membranes. (Adapted from FBrf0188584).
Notes on Group

The retm protein also contains a CRAL-TRIO motif, thought to mediate transport of small hydrophobic ligands (FBrf0188584).

Source Material
The PRELI-DOMAIN PROTEINS Gene Group has been compiled using the following publication(s): Dee and Moffat, 2005 .
Key Gene Ontology (GO) terms
Biological Process
Related Gene Groups
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
PRELID
PRELI-DOMAIN PROTEINS
Ups1p/PRELI-like proteins
Protein of Relevant Evolutionary and Lymphoid Interest
PRELI/MSF1
PRELI
Ups family of lipid transfer proteins
Secondary FlyBase ID(s)
References (2)