FB2026_02 , released June 18, 2026
Gene Group: MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS
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General Information
Name
MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS
Species
D. melanogaster
Symbol
MCU-CH
FlyBase ID
FBgg0002193
Date last reviewed
2026-03-26
Number of members
2
Description
Description
The mitochondrial calcium uniporter complex is a mitochondrial inner membrane calcium ion-activated channel that mediates the import of calcium ion from the cytosol into the mitochondrion. Reconstitution of the human uniporter requires two proteins, MCU and the metazoan-specific EMRE subunit. (Adapted from FBrf0233624).
Notes on Group
Source Material
The MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS Gene Group has been compiled using the following publication(s): Tufi et al., 2019 .
Key Gene Ontology (GO) terms
Molecular Function
calcium channel activity
Biological Process
mitochondrial calcium ion transmembrane transport
Cellular Component
mitochondrial inner membrane
Related Gene Groups
Parent group(s)
CALCIUM-ACTIVATED ION CHANNELS
CALCIUM CHANNEL SUBUNITS
Protein Complex group(s)
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEXES
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
MCU-CH
MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS
Secondary FlyBase ID(s)
References (2)