ORF2
110 (kD)
Parts of the 1731 element were demonstrated to encode peptides displaying reverse transcriptase activity. Antibodies were prepared against reverse transcriptase encoding peptides. The antibodies detect a protein of 110kD which was found in D. melanogaster cells but not cells of D. hydei or D. virilis. The protein cosediments with virus-like particles displaying reverse transcriptase activity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\1731\RTase using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\1731\RTase in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The protein co-sediments with virus-like particles that exhibit reverse transcriptase activity.