Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dfd::Ubx using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Dfd::Ubx in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Water activity differentially affects Dfd homeodomain and Ubx homeodomain DNA binding activity: formation of the Ubx HD-DNA complex is associated with significantly greater water release than that of the Dfd HD-DNA complex. Chimeric Ubx-Dfd homeodomains demonstrates the C terminal region of the Ubx HD is the primary determinant for the greater water release associated with DNA binding for the protein.
