FB2020_06, released Dec 22, 2020

Gene: Dmel\CG31191

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General Information
Symbol
Dmel\CG31191
Species
D. melanogaster
Name
Annotation Symbol
CG31191
Feature Type
protein_coding_gene
FlyBase ID
FBgn0051191
Gene Model Status
Current
Stock Availability
12 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
93A3-93A4
Sequence location
3R:20,909,213..20,945,530 [-]
Recombination map

3-69

RefSeq locus
NT_033777 REGION:20909213..20945530
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (0 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Summaries
    Gene Model and Products
    Number of Transcripts
    2
    Number of Unique Polypeptides
    2

    Please see the JBrowse view of Dmel\CG31191 for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Comments on Gene Model

    Stop-codon suppression (UGA) postulated (FBrf0222776, FlyBase analysis); supported by conservation of the extended ORF across Drosophila species (FBrf0202906).

    Gene model reviewed during 5.53

    gene_with_stop_codon_read_through ; SO:0000697

    Gene model reviewed during 6.02

    Sequence Ontology: Class of Gene
    gene_with_stop_codon_read_through
    (FlyBase Genome Annotators, 2013)
    nuclear_gene
    protein_coding_gene
    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    Assoc. CDS (aa)
    CG31191-RA
    FBtr0083984
    NM_169935
    4416
    255
    CG31191-RD
    FBtr0344322
    NM_001104380
    4416
    495
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Polypeptide Data
    Annotated Polypeptides
    Name
    FlyBase ID
    Predicted MW (kDa)
    Length (aa)
    Theoretical pI
    RefSeq ID
    GenBank
    CG31191-PA
    FBpp0083388
    29.8
    255
    9.74
    NP_732570
    AAF55822
    CG31191-PD
    FBpp0310710
    56.2
    495
    9.77
    NP_001097850
    ABW08712
    Polypeptides with Identical Sequences

    None of the polypeptides share 100% sequence identity.

    Additional Polypeptide Data and Comments
    Reported size (kDa)
    Comments
    External Data
    Crossreferences
    Linkouts
    Sequences Consistent with the Gene Model
    Mapped Features

    Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG31191 using the Feature Mapper tool.

    External Data
    Crossreferences
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Linkouts
    Expression Data
    Expression Summary Ribbons
    Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
    For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
    Transcript Expression
    in situ
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    wandering third instar larval stage
    wing pouch | restricted
    (Molnar et al., 2012)
    wing hinge primordium | restricted
    (Molnar et al., 2012)
    Additional Descriptive Data
    Marker for
     
    Subcellular Localization
    CV Term
    Polypeptide Expression
    mass spectroscopy
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    adult stage
    adult head
    (Aradska et al., 2015)
    Additional Descriptive Data
    Marker for
     
    Subcellular Localization
    CV Term
    Evidence
    References
    Expression Deduced from Reporters
    High-Throughput Expression Data
    Associated Tools

    GBrowse - Visual display of RNA-Seq signals

    View Dmel\CG31191 in GBrowse 2
    RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
    Bulk Downloads
    RNA-Seq RPKM values for all genes
    Reference
    See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
    Developmental Proteome: Life Cycle
    Developmental Proteome: Embryogenesis
    External Data and Images
    Linkouts
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    Images
    FlyBase Wiki
    Image Based Resources
    Alleles, Insertions, and Transgenic Constructs
    Classical and Insertion Alleles ( 17 )
    For All Classical and Insertion Alleles Show
     
    Other relevant insertions
    Transgenic Constructs ( 2 )
    For All Alleles Carried on Transgenic Constructs Show
    Transgenic constructs containing/affecting coding region of CG31191
    Transgenic constructs containing regulatory region of CG31191
    Deletions and Duplications ( 0 )
    Phenotypes
    For more details about a specific phenotype click on the relevant allele symbol.
    Lethality
    Allele
    partially lethal - majority die, with Scer\GAL4pnr-MD237
    viable
    viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
    Sterility
    Allele
    fertile
    Other Phenotypes
    Allele
    some die during pupal stage, with Scer\GAL4pnr-MD237
    visible, with Scer\GAL4pnr-MD237
    Phenotype manifest in
    Allele
    trichogen cell, with Scer\GAL4pnr-MD237
    Orthologs
    Downloads
    Download All DIOPT Orthologs
    Download All OrthoDB Orthologs
    Human Orthologs (via DIOPT v8.0)
    Homo sapiens (Human) (0)
    No records found.
    Model Organism Orthologs (via DIOPT v8.0)
    Mus musculus (laboratory mouse) (0)
    No records found.
    Rattus norvegicus (Norway rat) (0)
    No records found.
    Xenopus tropicalis (Western clawed frog) (0)
    No records found.
    Danio rerio (Zebrafish) (0)
    No records found.
    Caenorhabditis elegans (Nematode, roundworm) (1)
    Cele\F59B8.1
    8 of 15
    Yes
    Yes
    Arabidopsis thaliana (thale-cress) (0)
    No records found.
    Saccharomyces cerevisiae (Brewer's yeast) (0)
    No records found.
    Schizosaccharomyces pombe (Fission yeast) (0)
    No records found.
    Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190EG1 )
    Organism
    Common Name
    Gene
    AAA Syntenic Ortholog
    Multiple Dmel Genes in this Orthologous Group
    Drosophila suzukii
    Spotted wing Drosophila
    Dsuz\DS10_00009361
    Drosophila suzukii
    Spotted wing Drosophila
    Dsuz\DS10_00012990
    Drosophila simulans
    Dsim\GD20022
    Drosophila sechellia
    Dsec\GM15119
    Drosophila erecta
    Dere\GG15037
    Drosophila yakuba
    Dyak\GE27495
    Drosophila yakuba
    Dyak\GE25028
    Drosophila yakuba
    Dyak\GE11141
    Drosophila ananassae
    Dana\GF17007
    Drosophila pseudoobscura pseudoobscura
    Dpse\GA16079
    Drosophila persimilis
    Dper\GL23249
    Drosophila willistoni
    Dwil\GK22688
    Drosophila virilis
    Dvir\GJ14345
    Drosophila mojavensis
    Dmoj\GI21986
    Drosophila grimshawi
    Dgri\GH22279
    Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091509UM )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Musca domestica
    House fly
    Mdoa\17024991
    Glossina morsitans
    Tsetse fly
    Gmor\GMOY001515
    Lucilia cuprina
    Australian sheep blowfly
    Lcup\FF38_07886
    Aedes aegypti
    Yellow fever mosquito
    Aaeg\AAEL015650
    Anopheles darlingi
    American malaria mosquito
    Adar\ADAC004367
    Anopheles gambiae
    Malaria mosquito
    Agam\AGAP001581
    Culex quinquefasciatus
    Southern house mosquito
    Cqui\CPIJ013896
    Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0B0N )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Bombyx mori
    Silkmoth
    Bmor\BGIBMGA008112
    Danaus plexippus
    Monarch butterfly
    Dple\DPOGS208989-PA
    Heliconius melpomene
    Postman butterfly
    Hmel\HMEL016796
    Apis florea
    Little honeybee
    Aflo\2176170388
    Apis mellifera
    Western honey bee
    Amel\GB49664
    Bombus impatiens
    Common eastern bumble bee
    Bimp\BIMP20702
    Bombus terrestris
    Buff-tailed bumblebee
    Bter\15206099
    Linepithema humile
    Argentine ant
    Lhum\LH24517
    Megachile rotundata
    Alfalfa leafcutting bee
    Mrot\MROTU:00300e
    Nasonia vitripennis
    Parasitic wasp
    Nvit\Nasvi2EG008921
    Dendroctonus ponderosae
    Mountain pine beetle
    Dpod\YQE_08513
    Tribolium castaneum
    Red flour beetle
    Tcas\TC001064
    Pediculus humanus
    Human body louse
    Phum\PHUM222040
    Cimex lectularius
    Bed bug
    Clec\CLEC010880
    Acyrthosiphon pisum
    Pea aphid
    Apim\ACYPI002491
    Zootermopsis nevadensis
    Nevada dampwood termite
    Znev\Znev_07287
    Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0AXS )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strigamia maritima
    European centipede
    Smar\SMAR012460
    Strigamia maritima
    European centipede
    Smar\SMAR012462
    Ixodes scapularis
    Black-legged tick
    Isca\ISCW004271
    Ixodes scapularis
    Black-legged tick
    Isca\ISCW004269
    Tetranychus urticae
    Two-spotted spider mite
    Turt\tetur13g00860
    Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0HV9 )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\Sp-Hypp_2490
    Paralogs
    Downloads
    Download All DIOPT Paralogs
    Paralogs (via DIOPT v8.0)
    Drosophila melanogaster (Fruit fly) (0)
    No records found.
    Human Disease Associations
    FlyBase Human Disease Model Reports
      Disease Model Summary Ribbon
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Evidence
      References
      Potential Models Based on Orthology ( 0 )
      Human Ortholog
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Interaction
      References
      Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
      Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
      Homo sapiens (Human)
      Gene name
      Score
      OMIM
      OMIM Phenotype
      DO term
      Complementation?
      Transgene?
      Functional Complementation Data
      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
      Interactions
      Summary of Physical Interactions
      esyN Network Diagram
      Interactions Browser
      Summary of Genetic Interactions
      esyN Network Diagram
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      External Data
      Linkouts
      BioGRID - A database of protein and genetic interactions.
      DroID - A comprehensive database of gene and protein interactions.
      InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Pathways
      Signaling Pathways (FlyBase)
      Metabolic Pathways
      External Data
      Linkouts
      Genomic Location and Detailed Mapping Data
      Chromosome (arm)
      3R
      Recombination map

      3-69

      Cytogenetic map
      93A3-93A4
      Sequence location
      3R:20,909,213..20,945,530 [-]
      FlyBase Computed Cytological Location
      Cytogenetic map
      Evidence for location
      93A3-93A4
      Limits computationally determined from genome sequence between P{EP}SyndEP409 and P{lacW}l(3)j5C7j5C7
      Experimentally Determined Cytological Location
      Cytogenetic map
      Notes
      References
      Experimentally Determined Recombination Data
      Location

      3-69

      (FlyBase, 2016)

      3-73.3

      (Comeron et al., 2012)
      Left of (cM)
      Right of (cM)
      Notes
      Stocks and Reagents
      Stocks (12)
      Genomic Clones (42)
      cDNA Clones (33)
       

      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

      cDNA clones, fully sequenced
      BDGP DGC clones
      Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of
          Source for database merge of

          Source for merge of: CG17276 CG17277

          (FlyBase Genome Annotators, 2002-2003)
          Additional comments

          snoRNA:CG31191-a is encoded in an intron of CG31191.

          (Graveley et al., 2011)

          Annotations CG17276 and CG17277 merged as CG31191 in release 3 of the genome annotation.

          (FlyBase Genome Annotators, 2002-2003)
          Other Comments
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 35 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          KEGG Genes - Molecular building blocks of life in the genomic space.
          modMine - A data warehouse for the modENCODE project
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          FlyMine - An integrated database for Drosophila genomics
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Synonyms and Secondary IDs (3)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          References (39)