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FB2026_01
,
released March 12, 2026
fs(1)C2
Please see the JBrowse view of Dmel\dec2 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dec2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\dec2 in JBrowse1-23
1-23.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New annotation (CG33223) in release 3.2 of the genome annotation.
The 'dec2[1]' mutant allele had previously been assumed to be a strong hypomorphic mutation of the Cp36 gene encoding the s36 protein. However sequencing shows that 1. the 'dec2[1]' mutant chromosome contains a deletion that removes part of the CG33223 annotation, and 2. cDNA sequences of the transcripts encoded by the Cp36 gene are identical in Oregon-R and dec2[1] mutant females and are identical to the annotated transcript of the release 6.56 Cp36 gene annotation in FlyBase. In addition, immunochemical analysis indicates that the s36 protein encoded by the Cp36 gene is produced in dec2[1] mutant females (and there is no significant difference in the level of protein produced compared to Oregon-R), but that while the s36 protein forms insoluble aggregates in protein lysates of eggs of Oregon-R females, in eggs laid by dec2[1] mutant females the s36 protein is in the soluble fraction and is not detected in the eggshell. Thus the dec2[1] mutation does not appear to directly affect the Cp36 gene, but instead appears to be a mutation of CG33223, which may be involved in regulating (either directly or indirectly) the secretion of the s36 protein from follicle cells into the eggshell in the wild-type.
Source for identity of: dec2 CG33223
