Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data
obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the
literature.
Ncra\QS is a repressor of the Ncra\QF transcriptional activator, blocking its transactivation activity. It can thus be used to block Ncra\QF-driven expression of reporter constructs containing Ncra\QUAS regulatory sequences. Ncra\QS can be inhibited by the addition of quinic acid.