Open Close
General Information
Name
high-sugar diet, obesity
FlyBase ID
FBhh0000494
Disease Ontology Term
Parent Disease
OMIM
Overview

Flies fed a high-sugar diet at the larval or adult stages develop phenotypes typical of diabetes (see FBhh0000153, FBhh0000496) and phenotypes associated with obesity (this report); cardiomyopathy is also observed (see FBhh0000482). Epigenetic effects of parental diets high in sugar have also been studied in flies, showing increased susceptibility to obesity among offspring of males or females fed a high-sugar diet.

[updated Feb. 2017 by FlyBase; FBrf0222196]

Disease Summary Information
Disease Summary: high-sugar diet, obesity
OMIM report
Human gene(s) implicated
Symptoms and phenotype
Genetics
Cellular phenotype and pathology
Molecular information
External links
    Disease synonyms
    HS diet, obesity
    Ortholog Information
    Human gene(s) in FlyBase
      Other mammalian ortholog(s) used
        D. melanogaster Gene Information (0)
        Synthetic Gene(s) Used (0)
        Summary of Physical Interactions (0 groups)
        Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
        Genetic Tools, Stocks and Reagents
        Sources of Stocks
        Contact lab of origin for a reagent not available from a public stock center.
        Bloomington Stock Center Disease Page
        Selected mammalian transgenes
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila transgenes
        Allele
        Transgene
        Publicly Available Stocks
        RNAi constructs available
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila classical alleles
        Allele
        Allele class
        Mutagen
        Publicly Available Stocks
        References (45)