Name
autism spectrum disorder, susceptibility to, de novo coding mutations (postulated)
FlyBase ID
FBhh0001373
Disease Ontology Term
Parent Disease
A large-scale whole-exome study of families with a child diagnosed with autism spectrum disorder (ASD) has identified multiple de novo coding mutations potentially implicated in the development of ASD (pubmed:25363768). Human cDNAs incorporating these ASD-implicated variants have been introduced into flies (FBrf0237477) and will be available to interested researchers. See the table 'Disease-Implicated Variants' below.
[updated Jul. 2021 by FlyBase; FBrf0222196]
Disease Summary Information
Disease Summary: autism spectrum disorder, susceptibility to, de novo coding mutations (postulated)
Cellular phenotype and pathology
Other mammalian ortholog(s) used
D. melanogaster Gene Information
(0)
Other Genes Used: Viral, Bacterial, Synthetic (0)
Summary of Physical Interactions (0 groups)
Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
Alleles Representing Disease-Implicated Variants
