FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000062251
Interaction Network
Interactions Browser links
γTub23C network
Grip75 network
Reported Interactions
FBrf0107918-3.coIP.MW
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note

γtub

bait

Grip75

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

γTub23C and Grip75 coimmunoprecipitate and cosediment as part of the γTuRC (γ-tubulin ring complex).

FBrf0219801-32.CS.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

γ-tubulin

neutral component

γ-tubulin

neutral component

γ-tubulin

neutral component

Grip75

neutral component

Grip75

neutral component

Grip75

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; proteins produced from endogenous gene.

γTub23C and Grip75 co-fractionate as part of a Sas-4-containing S-γ-TuRC (γ-tubulin ring) complex.

Sas-4 complexes were immunoprecipitated from "high-speed lysates" depleted of mature centrosomes and different Sas-4-containing complexes were fractionated on a sucrose gradient.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)