FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
hppy, RagC-D
FlyBase ID
FBig0000095036
Interaction Network
Interactions Browser links
hppy network
RagC-D network
Reported Interactions
FBrf0211337-2.coIP.WB
Reference
Bryk et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
RagC-D 

dRagC

bait

FLAG tag

hppy 

MAP4K3

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Bryk et al., 2010)

hppy binds RagC-D more strongly than RagA-B

(Bryk et al., 2010)
FBrf0212911-1.PD.A
Reference
Resnik-Docampo and de Celis, 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
hppy 

MAP4K3

bait

GST pull down

RagC-D 

RagC

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Resnik-Docampo and de Celis, 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)