FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
hry, dgrn
FlyBase ID
FBig0000095077
Interaction Network
Interactions Browser links
hry network
dgrn network
Reported Interactions
FBrf0213366-2.PD.A
Reference
Abed et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dgrn 

Dgrn

bait

GST pull down

hry 

Hairy

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Abed et al., 2011)
FBrf0213366-3.PD.WB
Reference
Abed et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dgrn 

Dgrn

bait

GST pull down

dgrn 
hry 

Hairy

prey

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dgrn 
RING finger domain
unspecified role
aa 300-302

necessary, \'HC/AA\' is H300A, C302A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Abed et al., 2011)
FBrf0213366-5.Y2H
Reference
Abed et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
hry 

Hairy

bait
hry 
hry 
dgrn 

Dgrn

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
hry 
bHLH domain
unspecified role
hry 
bHLH, R33E
unspecified role
aa 33

necessary

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Prey was cloned reagent (previously isolated).

(Abed et al., 2011)

Two-hybrid system: yeast LexA/VP16.

(Abed et al., 2011)
FBrf0213366-8.ENZ.A
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dgrn 

Dgrn

enzyme
dgrn 

Dgrn

enzyme
dgrn 
hry 

Hairy

enzyme target

[35]S label

hry 

Hairy

enzyme target

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0213366-9.PD.A
Reference
Abed et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
hry 

Hairy

bait

GST pull down

hry 
hry 
dgrn 

Dgrn

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
hry 
N terminus
sufficient binding region
hry 
basic region
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Abed et al., 2011)
FBrf0213458-1.PD.A
Reference
Barry et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
hry 

Hairy

bait

GST pull down

dgrn 

Dgrn

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Barry et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)