FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000095181
Interaction Network
Interactions Browser links
Lar network
nerfin-2 network
Reported Interactions
FBrf0215568-10.SPR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Lar 

DLAR

bait

His tag

Lar 
Lar 

Nervous Fingers peptide

prey

phosphopeptide

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Lar 
D1 PTP domain
unspecified role
aa 1496-1731
Lar 
D2 PTP domain
unspecified role
aa 1760-2022
phosphotyrosine region
unspecified role
aa 246-256

VIGDpYVCRLCK

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Enzyme expressed and purified from bacteria.

Enzyme target derived from chemical synthesis.

Each of the D1 and D2 PTP domains can bind phosphopeptides independently, but with slightly different sequence specificities..

FBrf0215568-2.ENZ
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Lar 

DLAR

enzyme

His tag

Lar 

DLAR

enzyme

His tag

Lar 

Nervous Fingers peptide

enzyme target

phosphopeptide

Nervous Fingers peptide

enzyme target

phosphopeptide

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)