FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000095455
Interaction Network
Interactions Browser links
Ptp99A network
Abl network
Reported Interactions
FBrf0215568-16.SPR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

PTP99A

bait

His tag

Abl 

Abelson peptide

prey

phosphopeptide

Abl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
D1 PTP domain
unspecified role
aa 502-743
D2 PTP domain
unspecified role
aa 763-1018
Abl 
phosphotyrosine region
unspecified role
aa 536-545

RDDTpYTAHAG

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Enzyme expressed and purified from bacteria.

Enzyme target derived from chemical synthesis.

Each of the D1 and D2 PTP domains can bind phosphopeptides independently, but with slightly different sequence specificities..

FBrf0215568-8.ENZ
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

PTP99A

enzyme

His tag

PTP99A

enzyme

His tag

Abl 

Abelson peptide

enzyme target

phosphopeptide

Abl 

Abelson peptide

enzyme target

phosphopeptide

Abl 
Abl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)