FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cdk5, Mekk1
FlyBase ID
FBig0000095503
Interaction Network
Interactions Browser links
Cdk5 network
Mekk1 network
Reported Interactions
FBrf0217924-1.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cdk5 

CDK5

enzyme

His tag

Cdk5 

CDK5

enzyme

His tag

Mekk1 

MEKK1

enzyme target

FLAG tag

Mekk1 

MEKK1

enzyme target

FLAG tag

Mekk1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0217924-2.coIP.WB
Reference
Kang et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Mekk1 

MEKK1

bait

FLAG tag

Cdk5 

CDK5

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Bait expressed in transiently transfected HEK293 cells.

(Kang et al., 2012)

Prey expressed in transiently transfected HEK293 cells.

(Kang et al., 2012)

Hydrogen peroxide treatment enhances the interaction of Mekk1 and Cdk5.

(Kang et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)