FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Thor, eIF4E5
FlyBase ID
FBig0000095748
Interaction Network
Interactions Browser links
Thor network
eIF4E5 network
Reported Interactions
FBrf0184136-11.Y2H
Reference
Hernandez et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
eIF4E5 

4E5

bait

fused to GAL4 DNA-binding domain

Thor 

4EBP

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Hernandez et al., 2005)

Weak interaction.

(Hernandez et al., 2005)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Hernandez et al., 2005)
FBrf0219080-4.Y2H
Reference
Hernandez et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Thor 

4E-BP

bait

fused to GAL4 DNA-binding domain

eIF4E5 

eIF4E-5

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Thor interacts with eIF-4E, eIF4E-4 and eIF4E-5, but not with eIF4E-3, in the yeast two-hybrid system.

(Hernandez et al., 2012)

Two-hybrid system: yeast GAL4-BD/GAL4-AD.

(Hernandez et al., 2012)
FBrf0255793-4.Y2H
Reference
Shao et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Thor 

Thor

bait

fused to GAL4 DNA-binding domain

eIF4E5 

eIF4E-5

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Shao et al., 2023)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Shao et al., 2023)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)